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Begun in 1976 and expanded in 1989 and 2010, the Nurses’ Health Studies are the largest, longest-running investigations of health and wellness.

Findings from NHS contributed to the evidence base for developing the US Dietary Guidelines, Physical Activity Guidelines for Americans, and the Nutrition and Physical Activity Guidelines for Cancer Survivors. After the US Food and Drug Administration acted to ban dietary trans fats, based in part on evidence from NHS, estimates suggest that the population benefit is a decrease by more than 12% in the number of incident cases of diabetes and a more than 8% decrease in CVD. Read more about the history and key contributions of the Nurses’ Health Studies.